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Penile Cancer : Diagnosis and Treatment / Philippe E. Spiess

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Katalogangaben
MedienartE-Book [E-Book]
Titel Penile Cancer : Diagnosis and Treatment / Philippe E. Spiess
PersonSpiess, Philippe E. [Verfasser/in]
VeröffentlichungNew York, NY : Springer New York, 2016
Umfang / Format 1 Online-Ressource (155 p)
Ausgabe2nd ed
Anmerkungen Description based upon print version of record
SpracheEnglisch
ISBN9781493966790
9781493966776 (Sekundärausgabe)
Nummer965168607 (OCoLC)
EBC4747274 (EBC)
ebr11302585 (EBR)
MIL972751 (MYL)
EBL4747274 (EBL)
035326654 (EBP)
873885775 (K10Plus-Nummer)
Weitere AusgabeErscheint auch als Druck-Ausgabe: Penile Cancer : Diagnosis and Treatment
Schriftenreihe (Current Clinical Urology)
(Current Clinical Urology Ser.)
Schlagwörter Electronic books
Surgical oncology
Inhalt Preface -- Contents -- Abbreviations -- Contributors -- 1: Understanding the Pathophysiology of Penile Cancer and Its Preneoplastic Lesions -- Epidemiology of Penile Cancer -- Risk Factors for Penile Carcinoma -- Pathophysiology -- Human Papillomavirus -- HPV-Mediated Pathway -- HPV-Independent Pathway -- Penile Cancer Precursor Lesions -- Condyloma Acuminatum -- Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor) -- Bowenoid Papulosis -- Lichen Sclerosus (Balanitis Xerotica Obliterans) -- Carcinoma In Situ (Erythroplasia of Queyrat and Bowen's Disease) -- Histologic Subtypes; Conclusions -- References -- 2: Diagnostic Tools in the Evaluation and Management of Penile Cancer -- Introduction -- Novel Image-Based Diagnostic Tools -- Evaluation and Management of the Primary Penile Lesion -- Evaluation and Management of Loco-Regional Metastatic Lymphatic Spread -- Penile Cancer Biomarkers -- p53 -- p16INK4a -- Ki-67 -- Proliferating Cell Nuclear Antigen -- C-Reactive Protein -- Cyclin D1 -- Other Biomarkers -- Conclusions -- References -- 3: Penile-Sparing Surgical Approaches in the Management of Primary Penile Tumours -- Introduction -- Basis for Penile-Preserving Surgery; Topical Therapies -- Suitable for Stage Tis Disease Only -- 5 % 5-Fluorouracil (5-FU) -- Imiquimod -- Laser Therapy -- For Stage Tis, But Has Been Used Up to Stage T2 Lesions -- Penile-Sparing Surgical Techniques -- Circumcision -- For Lesions Confined to the Prepuce -- Total Glans Resurfacing -- For Glanular Tis/Ta and Up to Stage T1a Disease -- Partial Glans Resurfacing -- For Isolated Foci of Tis/Ta Affecting < 50 % of Glans -- Moh's Micrographic Surgery -- For Stage T1a, But Has Been Used Up to Stage T3 -- Wide Local Excision/Partial Glansectomy 
Inhalt For Small, Discrete Lesions on the Glans Up to Stage T1a -- Glansectomy and Reconstruction -- For Stage T1b/T2 Tumours Confined to the Glans -- Distal Corporectomy/Partial Penectomy and Reconstruction -- For Stage T2b/Distal T3 Disease -- Conclusions -- References -- 4: Dynamic Sentinel Node Biopsy and FDG-­PET/CT for Lymph Node Staging in Penile Cancer -- Introduction -- Risk-Adapted Approach -- Dynamic Sentinel Node Biopsy -- FDG-PET/CT -- Conclusion -- References; 5: Surgical Decision-Making, Technical Considerations, and Clinical Pearls in Therapeutic Inguinal Node Dissection for Penile Cancer -- Surgical Decision-Making in Patients with CN +ve Penile Cancer -- Unresectable Inguinal Lymphadenopathy -- Role of Systemic Therapy in High-Volume Lymph Node Metastasis -- Technical Considerations Among Patients Undergoing Lymphadenectomy for Clinically Positive Nodes -- Initial Resection of Clinically Mobile Nodes Less Than 4 cm with No Overlying Skin Fixation -- Perioperative Care -- Patient Position -- Skin Incision -- Surgical Boundaries; Clinically Node Positive Inguinal Field

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